BAPN으로 유도된 구개파열 백서의 osteonectin 발현 양상에 대한 연구
A study of osteonectin expression patterns in BAPN-induced cleft palate formed rats
태기출, 김은철, 이선경,
소속 상세정보
태기출 ( ) - 원광대학교 치과대학 교정학교실
김은철 ( ) - 원광대학교 치과대학 교정학교실
이선경 ( ) - 원광대학교 치과대학 교정학교실
KMID : 0361920000300040433
Abstract
The purpose of this study was to investigate osteonectin expression patterns in cleft palatecompare to normal palate rats. We used 4 pregnant rats, and beta-aminoproprionitrile was oral dose to rat according to lg/kg body weight at gestation days 13 to induce cleft palate. Total 6 fetus was got with cleft formed, then 3 fetus was used for immunohistostain and 3 fetus was used for western blot analysis. Expression patterns of osteonectin in mesenchymal cells of cleft palate was more dilute to mesenchymal cells of normal palate with immnunohistostain, and width and length of band of maxilla in cleft palate was more thin than maxilla of normal palate with western blot study.
키워드
구개파열;Osteonectin;면역조직화학;Western blot;Cleft palate;Osteonectin;Immunohistostaln;Western blot
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